Pathogenic Mechanisms Authors:
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چکیده
The outer blood-retinal barrier is formed, among its various components, by the RPE tight junctions. The intercellular cohesiveness of the RPE is not easily disrupted. Tight junctions appear as a necklace of strands that encircle each cell, binding each cell to its neighbors in a monolayer that separate the outer layer of the neural retina from the choriocapillaris(3). Choriocapillaris is a great vascular network of fenestrated capillaries with high blood flow, fundamental for the metabolism of outer retina. This outer blood-retinal barrier retards transepithelial diffusion through the paracellular spaces(3).
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تاریخ انتشار 2018